Cellulite is one of the biggest cosmetic challenges facing women. It’s a natural, normal part of the body’s development. However, millions of women see their curves in the mirror or photos and long for a smoother, firmer appearance. There’s nothing wrong with wanting to treat cellulite, as there’s nothing wrong with accepting it. For those who’ve been hunting for a simple, long-term solution for those ripples, QWO cellulite treatment may be the answer.

QWO (or collagenase clostridium histolyticum-aaes) is a recently FDA-approved injectable to treat cellulite in the buttocks. QWO contains a compound called collagenase. The collagenase breaks down these fibrous bands and helps redistribute the subcutaneous fat. The result is a smoother appearance with great long-term results.
QWO works in a similar fashion to dermal fillers or other injectables. It is a minimally invasive treatment and impacts the injected area without causing damage or side effects to the body.

More questions? Visit the QWO FAQ page.

Most women will have cellulite in their lifetime–about 9 out of 10 women.

That means your tough workouts and healthy eating habits are fantastic for your fitness and overall wellness—but won’t do much to reduce your cellulite.

If you really want to reduce cellulite, you need to understand what’s behind it.


Cellulite isn’t fat.


It isn’t caused by what, or how much you eat.


Or because you aren’t exercising enough.

Here’s what contributes to cellulite


Over time, skin thins.


Fat cells enlarge and push against the skin.


The fibrous bands under the skin thicken and cause tension—and the signature dimpling on your butt.


QWO is the first and only FDA-approved injectable for moderate to severe cellulite in the buttocks of adult women.

Visible results may be achieved in 10 weeks. In clinical studies, women received 3 treatments of QWO, 21 days apart.

QWO is injected by your aesthetic specialist directly into targeted dimples in the buttocks using a small needle.

You should not receive QWO if you are allergic to any collagenase or the ingredients in QWO, or have an active infection in the treatment area.

If your aesthetic specialist determines that QWO is right for you, she or he will decide on a treatment plan, including the total number of treatments.

Each treatment visit may include up to 2 treatment areas. QWO injections will be given 21 days apart for 3 treatment visits.

At each office visit, injections take as little as 10 minutes.

QWO may cause serious side effects including allergic (hypersensitivity) reactions, including anaphylaxis and injection site bruising.

The most common side effects of QWO include: injection site bruising, pain, areas of hardness, itching, redness, discoloration, swelling and warmth in the treatment area.

In clinical studies, side effects generally lasted less than 3 weeks.

These are not all the possible side effects of QWO.

QWO may cause serious side effects: allergic (hypersensitivity) reactions, including anaphylaxis and injection site bruising.
In clinical trials, women required no post-treatment downtime. Most bruising lessened after each treatment. Side effects generally lasted less than 3 weeks.

It’s not fully understood how QWO works in moderate to severe cellulite. The enzymes in QWO—called collagenases—are believed to target a structural cause under your skin.

It’s thought that QWO works in 3 ways: releasing fibrous bands, redistributing fat cells, and stimulating the growth of new collagen.

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